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Insights from the Molecular Modelling and Docking Analysis of AIF-NLS complex to infer Nuclear Translocation of the Protein
Apoptosis Inducing Factor protein has a dual role depending on its localization in mitochondrion (energy production) and nucleus (induces apoptosis). Cell damage transports this protein to nucleus which otherwise favors mitochondrion. The alteration of Nuclear Localisation Signal tags could aid nucl...
Autores principales: | Srivaths, Akash, Ramanathan, Shyam, Sakthivel, Seethalakshmi, Habeeb, SKM |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Biomedical Informatics
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953855/ https://www.ncbi.nlm.nih.gov/pubmed/29785072 http://dx.doi.org/10.6026/97320630014132 |
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