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Notoginsenoside R1 inhibits vascular smooth muscle cell proliferation, migration and neointimal hyperplasia through PI3K/Akt signaling

Restenosis caused by neointimal hyperplasia significantly decreases long-term efficacy of percutaneous transluminal angioplasty (PTA), stenting, and by-pass surgery for managing coronary and peripheral arterial diseases. A major cause of pathological neointima formation is abnormal vascular smooth m...

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Detalles Bibliográficos
Autores principales: Fang, Haihong, Yang, Shilin, Luo, Yingying, Zhang, Cheng, Rao, Yi, Liu, Renjing, Feng, Yulin, Yu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953917/
https://www.ncbi.nlm.nih.gov/pubmed/29765072
http://dx.doi.org/10.1038/s41598-018-25874-y