Determination of flumequine enantiomers and 7-hydroxyflumequine in water and sediment by chiral HPLC coupled with hybrid quadrupole-time-of-flight mass spectrometer

A liquid chromatography-tandem mass spectrometric (LC-MS/MS) method for simultaneous enantiomeric analysis of flumequine and its metabolite 7-hydroxyflumequine in water and sediment had been developed based on the separation method. Sediment samples were extracted with ACN and EDTA-Mcllvaine buffer...

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Detalles Bibliográficos
Autores principales: Xue, Moyong, Qin, Yuchang, Gu, Xu, Li, Junguo, Gao, Yunfeng, Yang, Xiaowei, Yao, Ting, Zhao, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953928/
https://www.ncbi.nlm.nih.gov/pubmed/29765079
http://dx.doi.org/10.1038/s41598-018-25889-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953928/
https://www.ncbi.nlm.nih.gov/pubmed/29765079
http://dx.doi.org/10.1038/s41598-018-25889-5

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