Importance of QT/RR hysteresis correction in studies of drug-induced QTc interval changes

QT/RR hysteresis and QT/RR adaptation are interlinked but separate physiological processes signifying how quickly and how much QT interval changes when heart rate changes, respectively. While QT interval duration is, as a rule, corrected for heart rate in terms of the QT/RR adaptation, the correctio...

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Detalles Bibliográficos
Autores principales: Malik, Marek, Garnett, Christine, Hnatkova, Katerina, Johannesen, Lars, Vicente, Jose, Stockbridge, Norman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953973/
https://www.ncbi.nlm.nih.gov/pubmed/29651591
http://dx.doi.org/10.1007/s10928-018-9587-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953973/
https://www.ncbi.nlm.nih.gov/pubmed/29651591
http://dx.doi.org/10.1007/s10928-018-9587-8

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