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Quantitative approach for cardiac risk assessment and interpretation in tuberculosis drug development
Cardiotoxicity is among the top drug safety concerns, and is of specific interest in tuberculosis, where this is a known or potential adverse event of current and emerging treatment regimens. As there is a need for a tool, beyond the QT interval, to quantify cardiotoxicity early in drug development,...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953981/ https://www.ncbi.nlm.nih.gov/pubmed/29520534 http://dx.doi.org/10.1007/s10928-018-9580-2 |