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Intrauterine smoke exposure deregulates lung function, pulmonary transcriptomes, and in particular insulin-like growth factor (IGF)-1 in a sex-specific manner

Prenatal exposure to tobacco smoke is a significant risk-factor for airway disease development. Furthermore, the high prevalence of pregnant smoking women requires the establishment of strategies for offspring lung protection. Therefore, we here aimed to understand the molecular mechanism of how pre...

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Detalles Bibliográficos
Autores principales: Dehmel, Stefan, Nathan, Petra, Bartel, Sabine, El-Merhie, Natalia, Scherb, Hagen, Milger, Katrin, John-Schuster, Gerrit, Yildirim, Ali Oender, Hylkema, Machteld, Irmler, Martin, Beckers, Johannes, Schaub, Bianca, Eickelberg, Oliver, Krauss-Etschmann, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953988/
https://www.ncbi.nlm.nih.gov/pubmed/29765129
http://dx.doi.org/10.1038/s41598-018-25762-5