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Intrauterine smoke exposure deregulates lung function, pulmonary transcriptomes, and in particular insulin-like growth factor (IGF)-1 in a sex-specific manner
Prenatal exposure to tobacco smoke is a significant risk-factor for airway disease development. Furthermore, the high prevalence of pregnant smoking women requires the establishment of strategies for offspring lung protection. Therefore, we here aimed to understand the molecular mechanism of how pre...
Autores principales: | Dehmel, Stefan, Nathan, Petra, Bartel, Sabine, El-Merhie, Natalia, Scherb, Hagen, Milger, Katrin, John-Schuster, Gerrit, Yildirim, Ali Oender, Hylkema, Machteld, Irmler, Martin, Beckers, Johannes, Schaub, Bianca, Eickelberg, Oliver, Krauss-Etschmann, Susanne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953988/ https://www.ncbi.nlm.nih.gov/pubmed/29765129 http://dx.doi.org/10.1038/s41598-018-25762-5 |
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