Pharmacodynamic modeling of cardiac biomarkers in breast cancer patients treated with anthracycline and trastuzumab regimens

Trastuzumab is associated with cardiotoxicity, manifesting as a decrease of the left-ventricular ejection fraction (LVEF). Administration of anthracyclines prior to trastuzumab increases risk of cardiotoxicity. High-sensitive troponin T and N-terminal-pro-brain natriuretic peptide (NT-proBNP) are mo...

Descripción completa

Detalles Bibliográficos
Autores principales: de Vries Schultink, Aurelia H. M., Boekhout, Annelies H., Gietema, Jourik A., Burylo, Artur M., Dorlo, Thomas P. C., van Hasselt, J. G. Coen, Schellens, Jan H. M., Huitema, Alwin D. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953989/
https://www.ncbi.nlm.nih.gov/pubmed/29429038
http://dx.doi.org/10.1007/s10928-018-9579-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953989/
https://www.ncbi.nlm.nih.gov/pubmed/29429038
http://dx.doi.org/10.1007/s10928-018-9579-8

Ejemplares similares