Potential of Murine IgG1 and Human IgG4 to Inhibit the Classical Complement and Fcγ Receptor Activation Pathways

IgG antibodies (Abs) mediate their effector functions through the interaction with Fcγ receptors (FcγRs) and the complement factors. The main IgG-mediated complement activation pathway is induced through the binding of complement C1q to IgG Abs. This interaction is dependent on antigen-dependent hex...

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Detalles Bibliográficos
Autores principales: Lilienthal, Gina-Maria, Rahmöller, Johann, Petry, Janina, Bartsch, Yannic C., Leliavski, Alexei, Ehlers, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954034/
https://www.ncbi.nlm.nih.gov/pubmed/29867943
http://dx.doi.org/10.3389/fimmu.2018.00958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954034/
https://www.ncbi.nlm.nih.gov/pubmed/29867943
http://dx.doi.org/10.3389/fimmu.2018.00958

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