IL-15 Overcomes Hepatocellular Carcinoma-Induced NK Cell Dysfunction

NK cells have potent antitumor capacity. They are enriched in the human liver, with a large subset specialized for tissue-residence. The potential for liver-resident versus liver-infiltrating NK cells to populate, and exert antitumor functions in, human liver tumors has not been studied. We examined...

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Detalles Bibliográficos
Autores principales: Easom, Nicholas J. W., Stegmann, Kerstin A., Swadling, Leo, Pallett, Laura J., Burton, Alice R., Odera, Dennis, Schmidt, Nathalie, Huang, Wei-Chen, Fusai, Giuseppe, Davidson, Brian, Maini, Mala K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954038/
https://www.ncbi.nlm.nih.gov/pubmed/29867983
http://dx.doi.org/10.3389/fimmu.2018.01009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954038/
https://www.ncbi.nlm.nih.gov/pubmed/29867983
http://dx.doi.org/10.3389/fimmu.2018.01009

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