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IL-15 Overcomes Hepatocellular Carcinoma-Induced NK Cell Dysfunction

NK cells have potent antitumor capacity. They are enriched in the human liver, with a large subset specialized for tissue-residence. The potential for liver-resident versus liver-infiltrating NK cells to populate, and exert antitumor functions in, human liver tumors has not been studied. We examined...

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Detalles Bibliográficos
Autores principales:	Easom, Nicholas J. W., Stegmann, Kerstin A., Swadling, Leo, Pallett, Laura J., Burton, Alice R., Odera, Dennis, Schmidt, Nathalie, Huang, Wei-Chen, Fusai, Giuseppe, Davidson, Brian, Maini, Mala K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954038/ https://www.ncbi.nlm.nih.gov/pubmed/29867983 http://dx.doi.org/10.3389/fimmu.2018.01009

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