DOT1L inhibition attenuates graft-versus-host disease by allogeneic T cells in adoptive immunotherapy models

Adoptive T-cell therapy is a promising therapeutic approach for cancer patients. The use of allogeneic T-cell grafts will improve its applicability and versatility provided that inherent allogeneic responses are controlled. T-cell activation is finely regulated by multiple signaling molecules that a...

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Detalles Bibliográficos
Autores principales: Kagoya, Yuki, Nakatsugawa, Munehide, Saso, Kayoko, Guo, Tingxi, Anczurowski, Mark, Wang, Chung-Hsi, Butler, Marcus O., Arrowsmith, Cheryl H., Hirano, Naoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954061/
https://www.ncbi.nlm.nih.gov/pubmed/29765028
http://dx.doi.org/10.1038/s41467-018-04262-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954061/
https://www.ncbi.nlm.nih.gov/pubmed/29765028
http://dx.doi.org/10.1038/s41467-018-04262-0

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