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Altered Maturation of Medullary TEC in EphB-Deficient Thymi Is Recovered by RANK Signaling Stimulation

In the present study, the relevance of EphB2 and EphB3 tyrosine kinase receptors for the maturation of medullary thymic epithelial cells (TECs) is analyzed. The absence of both molecules, but particularly that of EphB2, courses with altered maturation of medullary Cld3,4(hi)SSEA1(+) epithelial proge...

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Detalles Bibliográficos
Autores principales: Montero-Herradón, Sara, García-Ceca, Javier, Zapata, Agustín G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954084/
https://www.ncbi.nlm.nih.gov/pubmed/29867988
http://dx.doi.org/10.3389/fimmu.2018.01020