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Inhibition of Cathepsins B Induces Neuroprotection Against Secondary Degeneration in Ipsilateral Substantia Nigra After Focal Cortical Infarction in Adult Male Rats

Stroke is the leading cause of adult disability in the world. In general, recovery from stroke is incomplete. Accumulating evidences have shown that focal cerebral infarction leads to dynamic trans-neuronal degeneration in non-ischemic remote brain regions, with the disruption of connections to syna...

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Detalles Bibliográficos
Autores principales: Zuo, Xialin, Hou, Qinghua, Jin, Jizi, Chen, Xiaohui, Zhan, Lixuan, Tang, Yanyan, Shi, Zhe, Sun, Weiwen, Xu, En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954112/
https://www.ncbi.nlm.nih.gov/pubmed/29867438
http://dx.doi.org/10.3389/fnagi.2018.00125