GAS6/TAM Pathway Signaling in Hemostasis and Thrombosis

The GAS6/TYRO3-AXL-MERTK (TAM) signaling pathway is essential for full and sustained platelet activation, as well as thrombus stabilization. Inhibition of this pathway decreases platelet aggregation, shape change, clot retraction, aggregate formation under flow conditions, and surface expression of...

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Detalles Bibliográficos
Autores principales: Law, Luke A., Graham, Douglas K., Di Paola, Jorge, Branchford, Brian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954114/
https://www.ncbi.nlm.nih.gov/pubmed/29868590
http://dx.doi.org/10.3389/fmed.2018.00137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954114/
https://www.ncbi.nlm.nih.gov/pubmed/29868590
http://dx.doi.org/10.3389/fmed.2018.00137

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