Tracking HIV-1 recombination to resolve its contribution to HIV-1 evolution in natural infection

Recombination in HIV-1 is well documented, but its importance in the low-diversity setting of within-host diversification is less understood. Here we develop a novel computational tool (RAPR (Recombination Analysis PRogram)) to enable a detailed view of in vivo viral recombination during early infec...

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Detalles Bibliográficos
Autores principales: Song, Hongshuo, Giorgi, Elena E., Ganusov, Vitaly V., Cai, Fangping, Athreya, Gayathri, Yoon, Hyejin, Carja, Oana, Hora, Bhavna, Hraber, Peter, Romero-Severson, Ethan, Jiang, Chunlai, Li, Xiaojun, Wang, Shuyi, Li, Hui, Salazar-Gonzalez, Jesus F., Salazar, Maria G., Goonetilleke, Nilu, Keele, Brandon F., Montefiori, David C., Cohen, Myron S., Shaw, George M., Hahn, Beatrice H., McMichael, Andrew J., Haynes, Barton F., Korber, Bette, Bhattacharya, Tanmoy, Gao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954121/
https://www.ncbi.nlm.nih.gov/pubmed/29765018
http://dx.doi.org/10.1038/s41467-018-04217-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954121/
https://www.ncbi.nlm.nih.gov/pubmed/29765018
http://dx.doi.org/10.1038/s41467-018-04217-5

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