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Tissue and cellular rigidity and mechanosensitive signaling activation in Alexander disease

Glial cells have increasingly been implicated as active participants in the pathogenesis of neurological diseases, but critical pathways and mechanisms controlling glial function and secondary non-cell autonomous neuronal injury remain incompletely defined. Here we use models of Alexander disease, a...

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Detalles Bibliográficos
Autores principales: Wang, Liqun, Xia, Jing, Li, Jonathan, Hagemann, Tracy L., Jones, Jeffrey R., Fraenkel, Ernest, Weitz, David A., Zhang, Su-Chun, Messing, Albee, Feany, Mel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954157/
https://www.ncbi.nlm.nih.gov/pubmed/29765022
http://dx.doi.org/10.1038/s41467-018-04269-7