Establishing an academic biobank in a resource-challenged environment

Past practices of informal sample collections and spreadsheets for data and sample management fall short of best-practice models for biobanking, and are neither cost effective nor efficient to adequately serve the needs of large research studies. The biobank of the Sydney Brenner Institute for Molec...

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Autores principales: Soo, C C, Mukomana, F, Hazelhurst, S, Ramsay, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954164/
https://www.ncbi.nlm.nih.gov/pubmed/28604319
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author Soo, C C
Mukomana, F
Hazelhurst, S
Ramsay, M
author_facet Soo, C C
Mukomana, F
Hazelhurst, S
Ramsay, M
author_sort Soo, C C
collection PubMed
description Past practices of informal sample collections and spreadsheets for data and sample management fall short of best-practice models for biobanking, and are neither cost effective nor efficient to adequately serve the needs of large research studies. The biobank of the Sydney Brenner Institute for Molecular Bioscience serves as a bioresource for institutional, national and international research collaborations. It provides high-quality human biospecimens from African populations, secure data and sample curation and storage, as well as monitored sample handling and management processes, to promote both non-communicable and infectious-disease research. Best-practice guidelines have been adapted to align with a low-resource setting and have been instrumental in the development of a quality-management system, including standard operating procedures and a quality-control regimen. Here, we provide a summary of 10 important considerations for initiating and establishing an academic research biobank in a low-resource setting. These include addressing ethical, legal, technical, accreditation and/or certification concerns and financial sustainability.
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spelling pubmed-59541642018-05-16 Establishing an academic biobank in a resource-challenged environment Soo, C C Mukomana, F Hazelhurst, S Ramsay, M S Afr Med J Article Past practices of informal sample collections and spreadsheets for data and sample management fall short of best-practice models for biobanking, and are neither cost effective nor efficient to adequately serve the needs of large research studies. The biobank of the Sydney Brenner Institute for Molecular Bioscience serves as a bioresource for institutional, national and international research collaborations. It provides high-quality human biospecimens from African populations, secure data and sample curation and storage, as well as monitored sample handling and management processes, to promote both non-communicable and infectious-disease research. Best-practice guidelines have been adapted to align with a low-resource setting and have been instrumental in the development of a quality-management system, including standard operating procedures and a quality-control regimen. Here, we provide a summary of 10 important considerations for initiating and establishing an academic research biobank in a low-resource setting. These include addressing ethical, legal, technical, accreditation and/or certification concerns and financial sustainability. 2017-05-24 /pmc/articles/PMC5954164/ /pubmed/28604319 Text en http://creativecommons.org/licenses/by-nc/4.0/ This open-access article is distributed under Creative Commons licence CC-BY-NC 4.0.
spellingShingle Article
Soo, C C
Mukomana, F
Hazelhurst, S
Ramsay, M
Establishing an academic biobank in a resource-challenged environment
title Establishing an academic biobank in a resource-challenged environment
title_full Establishing an academic biobank in a resource-challenged environment
title_fullStr Establishing an academic biobank in a resource-challenged environment
title_full_unstemmed Establishing an academic biobank in a resource-challenged environment
title_short Establishing an academic biobank in a resource-challenged environment
title_sort establishing an academic biobank in a resource-challenged environment
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954164/
https://www.ncbi.nlm.nih.gov/pubmed/28604319
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