RECON-Dependent Inflammation in Hepatocytes Enhances Listeria monocytogenes Cell-to-Cell Spread

The oxidoreductase RECON is a high-affinity cytosolic sensor of bacterium-derived cyclic dinucleotides (CDNs). CDN binding inhibits RECON’s enzymatic activity and subsequently promotes inflammation. In this study, we sought to characterize the effects of RECON on the infection cycle of the intracell...

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Detalles Bibliográficos
Autores principales: McFarland, Adelle P., Burke, Thomas P., Carletti, Alexie A., Glover, Rochelle C., Tabakh, Hannah, Welch, Matthew D., Woodward, Joshua J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954220/
https://www.ncbi.nlm.nih.gov/pubmed/29764944
http://dx.doi.org/10.1128/mBio.00526-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954220/
https://www.ncbi.nlm.nih.gov/pubmed/29764944
http://dx.doi.org/10.1128/mBio.00526-18

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