The Anti-neuroinflammatory Activity of Tectorigenin Pretreatment via Downregulated NF-κB and ERK/JNK Pathways in BV-2 Microglial and Microglia Inactivation in Mice With Lipopolysaccharide

The activation of microglia is decisively involved with the neurodegeneration observed in many neuroinflammatory pathologies, such as multiple sclerosis, Parkinson’s disease, and Alzheimer’s disease. Tectorigenin (TEC) is an isoflavone isolated from various medicinal plants, such as Pueraria thunber...

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Detalles Bibliográficos
Autores principales: Lim, Hye-Sun, Kim, Yu Jin, Kim, Bu-Yeo, Park, Gunhyuk, Jeong, Soo-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954245/
https://www.ncbi.nlm.nih.gov/pubmed/29867470
http://dx.doi.org/10.3389/fphar.2018.00462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954245/
https://www.ncbi.nlm.nih.gov/pubmed/29867470
http://dx.doi.org/10.3389/fphar.2018.00462

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