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GRIM-Filter: Fast seed location filtering in DNA read mapping using processing-in-memory technologies

BACKGROUND: Seed location filtering is critical in DNA read mapping, a process where billions of DNA fragments (reads) sampled from a donor are mapped onto a reference genome to identify genomic variants of the donor. State-of-the-art read mappers 1) quickly generate possible mapping locations for s...

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Detalles Bibliográficos
Autores principales: Kim, Jeremie S., Senol Cali, Damla, Xin, Hongyi, Lee, Donghyuk, Ghose, Saugata, Alser, Mohammed, Hassan, Hasan, Ergin, Oguz, Alkan, Can, Mutlu, Onur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954284/
https://www.ncbi.nlm.nih.gov/pubmed/29764378
http://dx.doi.org/10.1186/s12864-018-4460-0