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Efficient algorithms for polyploid haplotype phasing

BACKGROUND: Inference of haplotypes, or the sequence of alleles along the same chromosomes, is a fundamental problem in genetics and is a key component for many analyses including admixture mapping, identifying regions of identity by descent and imputation. Haplotype phasing based on sequencing read...

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Detalles Bibliográficos
Autores principales: He, Dan, Saha, Subrata, Finkers, Richard, Parida, Laxmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954289/
https://www.ncbi.nlm.nih.gov/pubmed/29764364
http://dx.doi.org/10.1186/s12864-018-4464-9