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Protective Role of Myeloid Cells Expressing a G-CSF Receptor Polymorphism in an Induced Model of Lupus

The genetic analysis of the lupus-prone NZM2410 mouse has identified a suppressor locus, Sle2c2, which confers resistance to spontaneous lupus in combination with NZM2410 susceptibility loci, or in the chronic graft-versus-host disease (cGVHD) induced model of lupus in the B6.Sle2c2 congenic strain....

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Detalles Bibliográficos
Autores principales: Sivakumar, Ramya, Abboud, Georges, Mathews, Clayton E., Atkinson, Mark A., Morel, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954343/
https://www.ncbi.nlm.nih.gov/pubmed/29868014
http://dx.doi.org/10.3389/fimmu.2018.01053