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Activated prothrombin complex concentrate to reverse the factor Xa inhibitor (apixaban) effect before emergency surgery: a case series

BACKGROUND: The lack of an antidote against factor Xa inhibitors in case of major bleeding or need for urgent surgery is a concern to clinicians. Guidelines on managing major bleeding in patients under anticoagulation with a factor Xa inhibitor suggest several hemostatic agents to reverse the effect...

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Detalles Bibliográficos
Autores principales: Schultz, Nina Haagenrud, Lundblad, Runar, Holme, Pål Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954448/
https://www.ncbi.nlm.nih.gov/pubmed/29764497
http://dx.doi.org/10.1186/s13256-018-1660-9