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The Plasticity of CD4(+)CD25(+)FOXP3(+)CD127(low) T Cells in Patients with Metastatic Renal Cell Carcinoma in the Course of Interferon-Alpha Immunotherapy

AIMS: To examine changes in subpopulation of CD4(+)CD25(+)Foxp3(+)CD127(low) T lymphocytes (Treg) and their association with the efficiency of the IFN-α therapy. MATERIALS AND METHODS: Pts with mRCC who had undergone nephrectomy were treated with IFN-α at a dose of 6 × 10(6) U/day three times a week...

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Detalles Bibliográficos
Autores principales: Sayapina, Maria S., Bykovskaia, Svetlana N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954933/
https://www.ncbi.nlm.nih.gov/pubmed/29853890
http://dx.doi.org/10.1155/2018/7828735