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Carnosic Acid, a Natural Diterpene, Attenuates Arsenic-Induced Hepatotoxicity via Reducing Oxidative Stress, MAPK Activation, and Apoptotic Cell Death Pathway

The present studies have been executed to explore the protective mechanism of carnosic acid (CA) against NaAsO(2)-induced hepatic injury. CA exhibited a concentration dependent (1–4 μM) increase in cell viability against NaAsO(2) (12 μM) in murine hepatocytes. NaAsO(2) treatment significantly enhanc...

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Detalles Bibliográficos
Autores principales: Das, Sonjit, Joardar, Swarnalata, Manna, Prasenjit, Dua, Tarun K., Bhattacharjee, Niloy, Khanra, Ritu, Bhowmick, Shovonlal, Kalita, Jatin, Saha, Achintya, Ray, Supratim, De Feo, Vincenzo, Dewanjee, Saikat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954942/
https://www.ncbi.nlm.nih.gov/pubmed/29854073
http://dx.doi.org/10.1155/2018/1421438