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Levels of miR-126 and miR-218 are elevated in ductal carcinoma in situ (DCIS) and inhibit malignant potential of DCIS derived cells

A substantial number of ductal carcinoma in situ (DCIS) detected by mammography never progress to invasive ductal carcinoma (IDC) and current approaches fail to identify low-risk patients not at need of adjuvant therapies. We aimed to identify the key miRNAs protecting DCIS from malignant evolution,...

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Detalles Bibliográficos
Autores principales: Volinia, Stefano, Bertagnolo, Valeria, Grassilli, Silvia, Brugnoli, Federica, Manfrini, Marco, Galasso, Marco, Scatena, Cristian, Mazzanti, Chiara Maria, Lessi, Francesca, Naccarato, Giuseppe, Caligo, Adelaide, Bianchini, Enzo, Piubello, Quirino, Orvieto, Enrico, Rugge, Massimo, Natali, Cristina, Reale, Domenico, Vecchione, Andrea, Warner, Sarah, Croce, Carlo Maria, Capitani, Silvano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955110/
https://www.ncbi.nlm.nih.gov/pubmed/29805754
http://dx.doi.org/10.18632/oncotarget.25261