miRNA122a regulation of gene therapy vectors targeting hepatocellular cancer stem cells

In this study, we report a miRNA122a based targeted gene therapy for hepatocellular cancer stem cells (CSCs). First, we assessed the levels of miRNA122a in normal human hepatocytes, a panel of hepatocellular carcinoma (HCC) cell lines and hepatocellular CSCs observing its significant downregulation...

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Detalles Bibliográficos
Autores principales: Dhungel, Bijay, Ramlogan-Steel, Charmaine A., Layton, Christopher J., Steel, Jason C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955118/
https://www.ncbi.nlm.nih.gov/pubmed/29805757
http://dx.doi.org/10.18632/oncotarget.25280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955118/
https://www.ncbi.nlm.nih.gov/pubmed/29805757
http://dx.doi.org/10.18632/oncotarget.25280

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