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The receptor protein tyrosine phosphatase PTPRJ negatively modulates the CD98hc oncoprotein in lung cancer cells

PTPRJ, a receptor protein tyrosine phosphatase strongly downregulated in human cancer, displays tumor suppressor activity by negatively modulating several proteins involved in proliferating signals. Here, through a proteomic-based approach, we identified a list of potential PTPRJ-interacting protein...

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Detalles Bibliográficos
Autores principales: D’Agostino, Sabrina, Lanzillotta, Delia, Varano, Mariaconcetta, Botta, Cirino, Baldrini, Antonio, Bilotta, Anna, Scalise, Stefania, Dattilo, Vincenzo, Amato, Rosario, Gaudio, Eugenio, Paduano, Francesco, Palmieri, Camillo, Iuliano, Rodolfo, Perrotti, Nicola, Indiveri, Cesare, Fusco, Alfredo, Gaspari, Marco, Trapasso, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955124/
https://www.ncbi.nlm.nih.gov/pubmed/29805737
http://dx.doi.org/10.18632/oncotarget.25101