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A new metabolic gene signature in prostate cancer regulated by JMJD3 and EZH2

Histone methylation is essential for gene expression control. Trimethylated lysine 27 of histone 3 (H3K27me3) is controlled by the balance between the activities of JMJD3 demethylase and EZH2 methyltransferase. This epigenetic mark has been shown to be deregulated in prostate cancer, and evidence sh...

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Detalles Bibliográficos
Autores principales: Daures, Marine, Idrissou, Mouhamed, Judes, Gaëlle, Rifaï, Khaldoun, Penault-Llorca, Frédérique, Bignon, Yves-Jean, Guy, Laurent, Bernard-Gallon, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955128/
https://www.ncbi.nlm.nih.gov/pubmed/29805743
http://dx.doi.org/10.18632/oncotarget.25182