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A new metabolic gene signature in prostate cancer regulated by JMJD3 and EZH2
Histone methylation is essential for gene expression control. Trimethylated lysine 27 of histone 3 (H3K27me3) is controlled by the balance between the activities of JMJD3 demethylase and EZH2 methyltransferase. This epigenetic mark has been shown to be deregulated in prostate cancer, and evidence sh...
Autores principales: | Daures, Marine, Idrissou, Mouhamed, Judes, Gaëlle, Rifaï, Khaldoun, Penault-Llorca, Frédérique, Bignon, Yves-Jean, Guy, Laurent, Bernard-Gallon, Dominique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955128/ https://www.ncbi.nlm.nih.gov/pubmed/29805743 http://dx.doi.org/10.18632/oncotarget.25182 |
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