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Methylation of DNA and chromatin as a mechanism of oncogenesis and therapeutic target in neuroblastoma

Neuroblastoma (NB), a developmental cancer, is often fatal, emphasizing the need to understand its pathogenesis and identify new therapeutic targets. The heterogeneous pathological and clinical phenotype of NB underscores the cryptic biological and genetic features of this tumor that result in outco...

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Detalles Bibliográficos
Autores principales: Ram Kumar, Ram Mohan, Schor, Nina Felice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955135/
https://www.ncbi.nlm.nih.gov/pubmed/29774131
http://dx.doi.org/10.18632/oncotarget.25084