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Proteomic profiling of skeletal and cardiac muscle in cancer cachexia: alterations in sarcomeric and mitochondrial protein expression

BACKGROUND: Cancer cachexia is observed in more than 50% of advanced cancer patients, and impairs quality of life and prognosis. A variety of pathways are likely to be dysregulated. Hence, a broad-spectrum understanding of the disease process is best achieved by a discovery based approach such as pr...

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Detalles Bibliográficos
Autores principales: Shum, Angie M. Y., Poljak, Anne, Bentley, Nicholas L., Turner, Nigel, Tan, Timothy C., Polly, Patsie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955146/
https://www.ncbi.nlm.nih.gov/pubmed/29774118
http://dx.doi.org/10.18632/oncotarget.25146