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Ceragenin CSA-13 as free molecules and attached to magnetic nanoparticle surfaces induce caspase-dependent apoptosis in human breast cancer cells via disruption of cell oxidative balance

Natural antimicrobial peptides and ceragenins, as non-peptide amphipathic mimics, have been proposed as anti-cancer agents. To date, it has been confirmed that cathelicidin LL-37 and ceragenin CSA-13, both in free form and immobilized on the surface of magnetic nanoparticles (MNP@LL-37, MNP@CSA-13)...

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Detalles Bibliográficos
Autores principales: Piktel, Ewelina, Prokop, Izabela, Wnorowska, Urszula, Król, Grzegorz, Cieśluk, Mateusz, Niemirowicz, Katarzyna, Savage, Paul B., Bucki, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955147/
https://www.ncbi.nlm.nih.gov/pubmed/29774111
http://dx.doi.org/10.18632/oncotarget.25105