Cargando…

Ceragenin CSA-13 as free molecules and attached to magnetic nanoparticle surfaces induce caspase-dependent apoptosis in human breast cancer cells via disruption of cell oxidative balance

Natural antimicrobial peptides and ceragenins, as non-peptide amphipathic mimics, have been proposed as anti-cancer agents. To date, it has been confirmed that cathelicidin LL-37 and ceragenin CSA-13, both in free form and immobilized on the surface of magnetic nanoparticles (MNP@LL-37, MNP@CSA-13)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Piktel, Ewelina, Prokop, Izabela, Wnorowska, Urszula, Król, Grzegorz, Cieśluk, Mateusz, Niemirowicz, Katarzyna, Savage, Paul B., Bucki, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955147/ https://www.ncbi.nlm.nih.gov/pubmed/29774111 http://dx.doi.org/10.18632/oncotarget.25105

Ejemplares similares

Ceragenin CSA-13 displays high antibacterial efficiency in a mouse model of urinary tract infection
por: Wnorowska, Urszula, et al.
Publicado: (2022)

Sporicidal activity of ceragenin CSA-13 against Bacillus subtilis
por: Piktel, Ewelina, et al.
Publicado: (2017)

Formulation and candidacidal activity of magnetic nanoparticles coated with cathelicidin LL-37 and ceragenin CSA-13
por: Niemirowicz, Katarzyna, et al.
Publicado: (2017)

Use of ceragenins as a potential treatment for urinary tract infections
por: Wnorowska, Urszula, et al.
Publicado: (2019)

Ceragenins and Ceragenin-Based Core-Shell Nanosystems as New Antibacterial Agents against Gram-Negative Rods Causing Nosocomial Infections
por: Karasiński, Maciej, et al.
Publicado: (2023)

NDM-1 Carbapenemase-Producing Enterobacteriaceae are Highly Susceptible to Ceragenins CSA-13, CSA-44, and CSA-131
por: Chmielewska, Sylwia Joanna, et al.
Publicado: (2020)

Quantification of Synergistic Effects of Ceragenin CSA-131 Combined with Iron Oxide Magnetic Nanoparticles Against Cancer Cells
por: Piktel, Ewelina, et al.
Publicado: (2020)

Candidacidal Activity of Selected Ceragenins and Human Cathelicidin LL-37 in Experimental Settings Mimicking Infection Sites
por: Durnaś, Bonita, et al.
Publicado: (2016)

Bactericidal activity and biocompatibility of ceragenin-coated magnetic nanoparticles
por: Niemirowicz, Katarzyna, et al.
Publicado: (2015)

Magnetic nanoparticles enhance the anticancer activity of cathelicidin LL-37 peptide against colon cancer cells
por: Niemirowicz, Katarzyna, et al.
Publicado: (2015)

Nanoantibiotics containing membrane-active human cathelicidin LL-37 or synthetic ceragenins attached to the surface of magnetic nanoparticles as novel and innovative therapeutic tools: current status and potential future applications
por: Wnorowska, Urszula, et al.
Publicado: (2020)

Mechanical Properties of the Extracellular Environment of Human Brain Cells Drive the Effectiveness of Drugs in Fighting Central Nervous System Cancers
por: Cieśluk, Mateusz, et al.
Publicado: (2022)

Ceragenin-Coated Non-Spherical Gold Nanoparticles as Novel Candidacidal Agents
por: Skłodowski, Karol, et al.
Publicado: (2021)

Assessment of Ceragenins in Prevention of Damage to Voice Prostheses Caused by Candida Biofilm Formation
por: Spałek, Jakub, et al.
Publicado: (2021)

Anaerobic bacteria growth in the presence of cathelicidin LL-37 and selected ceragenins delivered as magnetic nanoparticles cargo
por: Durnaś, Bonita, et al.
Publicado: (2017)

Bactericidal Properties of Rod-, Peanut-, and Star-Shaped Gold Nanoparticles Coated with Ceragenin CSA-131 against Multidrug-Resistant Bacterial Strains
por: Chmielewska, Sylwia Joanna, et al.
Publicado: (2021)

Peanut-Shaped Gold Nanoparticles with Shells of Ceragenin CSA-131 Display the Ability to Inhibit Ovarian Cancer Growth In Vitro and in a Tumor Xenograft Model
por: Piktel, Ewelina, et al.
Publicado: (2021)

Recombinant Human Plasma Gelsolin Stimulates Phagocytosis while Diminishing Excessive Inflammatory Responses in Mice with Pseudomonas aeruginosa Sepsis
por: Piktel, Ewelina, et al.
Publicado: (2020)

Inhibition of inflammatory response in human keratinocytes by magnetic nanoparticles functionalized with PBP10 peptide derived from the PIP2-binding site of human plasma gelsolin
por: Piktel, Ewelina, et al.
Publicado: (2019)

Ceragenin CSA-44 as a Means to Control the Formation of the Biofilm on the Surface of Tooth and Composite Fillings
por: Tokajuk, Joanna, et al.
Publicado: (2022)

Glyoxylate Shunt and Pyruvate-to-Acetoin Shift Are Specific Stress Responses Induced by Colistin and Ceragenin CSA-13 in Enterobacter hormaechei ST89
por: Prasad, Suhanya V., et al.
Publicado: (2023)

Core–shell magnetic nanoparticles display synergistic antibacterial effects against Pseudomonas aeruginosa and Staphylococcus aureus when combined with cathelicidin LL-37 or selected ceragenins
por: Niemirowicz, Katarzyna, et al.
Publicado: (2016)

Sphingosine-1-Phosphate-Triggered Expression of Cathelicidin LL-37 Promotes the Growth of Human Bladder Cancer Cells
por: Wollny, Tomasz, et al.
Publicado: (2022)

Inhomogeneity of stiffness and density of the extracellular matrix within the leukoplakia of human oral mucosa as potential physicochemical factors leading to carcinogenesis
por: Pogoda, Katarzyna, et al.
Publicado: (2021)

N-Acetyl-Cysteine Increases Activity of Peanut-Shaped Gold Nanoparticles Against Biofilms Formed by Clinical Strains of Pseudomonas aeruginosa Isolated from Sputum of Cystic Fibrosis Patients
por: Piktel, Ewelina, et al.
Publicado: (2022)

The Role of Cathelicidin LL-37 in Cancer Development
por: Piktel, Ewelina, et al.
Publicado: (2015)

Antibacterial and Antifungal Activities of Poloxamer Micelles Containing Ceragenin CSA-131 on Ciliated Tissues
por: Hashemi, Marjan M., et al.
Publicado: (2018)

Use of magnetic nanoparticles as a drug delivery system to improve chlorhexidine antimicrobial activity
por: Tokajuk, Grażyna, et al.
Publicado: (2017)

Hypogelsolinemia and Decrease in Blood Plasma Sphingosine-1-Phosphate in Patients Diagnosed with Severe Acute Pancreatitis
por: Wollny, Tomasz, et al.
Publicado: (2021)

Bactericidal Activity of Ceragenin in Combination with Ceftazidime, Levofloxacin, Co-Trimoxazole, and Colistin against the Opportunistic Pathogen Stenotrophomonas maltophilia
por: Paprocka, Paulina, et al.
Publicado: (2022)

Potential Synergy Activity of the Novel Ceragenin, CSA-13, against Carbapenem-Resistant Acinetobacter baumannii Strains Isolated from Bacteremia Patients
por: Bozkurt-Guzel, Cagla, et al.
Publicado: (2014)

Quantification of Synergistic Effects of Ceragenin CSA-131 Combined with Iron Oxide Magnetic Nanoparticles Against Cancer Cells [Corrigendum]
Publicado: (2023)

Targeting the Gut Microbiota to Relieve the Symptoms of Irritable Bowel Syndrome
por: Wollny, Tomasz, et al.
Publicado: (2021)

New β-Lactam Antibiotics and Ceragenins – A Study to Assess Their Potential in Treatment of Infections Caused by Multidrug-Resistant Strains of Pseudomonas aeruginosa
por: Paprocka, Paulina, et al.
Publicado: (2021)

Bacteria Residing at Root Canals Can Induce Cell Proliferation and Alter the Mechanical Properties of Gingival and Cancer Cells
por: Suprewicz, Łukasz, et al.
Publicado: (2020)

Recent insights in nanotechnology-based drugs and formulations designed for effective anti-cancer therapy
por: Piktel, Ewelina, et al.
Publicado: (2016)

Bactericidal and immunomodulatory properties of magnetic nanoparticles functionalized by 1,4-dihydropyridines
por: Niemirowicz-Laskowska, Katarzyna, et al.
Publicado: (2018)

Physics Comes to the Aid of Medicine—Clinically-Relevant Microorganisms through the Eyes of Atomic Force Microscope
por: Cieśluk, Mateusz, et al.
Publicado: (2020)

In Vitro Bactericidal and Bacteriolytic Activity of Ceragenin CSA-13 against Planktonic Cultures and Biofilms of Streptococcus pneumoniae and Other Pathogenic Streptococci
por: Moscoso, Miriam, et al.
Publicado: (2014)

Ceragenins exhibit bactericidal properties that are independent of the ionic strength in the environment mimicking cystic fibrosis sputum
por: Skłodowski, Karol, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_okaoovj1s9ij95f8ptm7t7vaqd