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SIK2 attenuates proliferation and survival of breast cancer cells with simultaneous perturbation of MAPK and PI3K/Akt pathways

Salt Inducible Kinase2 (SIK2) has been shown to contribute to tumorigenesis in multiple tumor types in a dichotomous manner. However, little is known about its contribution to breast malignancies. Here, we report SIK2 as a potential tumor suppressor in breast cancer whose expression was reduced in t...

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Detalles Bibliográficos
Autores principales: Zohrap, Neslihan, Saatci, Özge, Ozes, Burcak, Coban, Ipek, Atay, Hasan Murat, Battaloglu, Esra, Şahin, Özgür, Bugra, Kuyas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955149/
https://www.ncbi.nlm.nih.gov/pubmed/29774109
http://dx.doi.org/10.18632/oncotarget.25082