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Pre-clinical activity of targeting the PI3K/Akt/mTOR pathway in Burkitt lymphoma
Though outcomes for pediatric Burkitt lymphoma (BL) have improved significantly in recent decades with intensive multi-agent chemotherapy and the addition of rituximab, chemotherapy resistance remains a significant impediment to cure following relapse. Activation of the PI3K/AKT pathway has been imp...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955151/ https://www.ncbi.nlm.nih.gov/pubmed/29774105 http://dx.doi.org/10.18632/oncotarget.25072 |