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MiR-33 promotes myocardial fibrosis by inhibiting MMP16 and stimulating p38 MAPK signaling

Myocardial fibrosis occurs in the late stages of many cardiovascular diseases, and appears to be stimulated by various microRNAs (miRNAs). We previously found that miR-33 may stimulate cardiac remodeling. Here, we examined the involvement of miR-33 in myocardial fibrosis. Proximal left coronary desc...

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Detalles Bibliográficos
Autores principales: Chen, Zhen, Ding, Hua-Sheng, Guo, Xin, Shen, Jing-Jing, Fan, Di, Huang, Yan, Huang, Cong-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955156/
https://www.ncbi.nlm.nih.gov/pubmed/29774121
http://dx.doi.org/10.18632/oncotarget.25173