Vorapaxar treatment reduces mesangial expansion in streptozotocin-induced diabetic nephropathy in mice

BACKGROUND: Twenty years after the onset of diabetes, up to 40% of patients develop diabetic nephropathy. Protease-activated receptor-1 (PAR-1) has recently been shown to aggravate the development of experimental diabetic nephropathy. PAR-1 deficient mice develop less albuminuria and glomerular lesi...

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Detalles Bibliográficos
Autores principales: Waasdorp, Maaike, Duitman, JanWillem, Florquin, Sandrine, Spek, C. Arnold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper: Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955164/
https://www.ncbi.nlm.nih.gov/pubmed/29774092
http://dx.doi.org/10.18632/oncotarget.25069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955164/
https://www.ncbi.nlm.nih.gov/pubmed/29774092
http://dx.doi.org/10.18632/oncotarget.25069

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