Prefrontal GABA levels, hippocampal resting perfusion and the risk of psychosis

Preclinical models propose that the onset of psychosis is associated with hippocampal hyperactivity, thought to be driven by cortical GABAergic interneuron dysfunction and disinhibition of pyramidal neurons. Recent neuroimaging studies suggest that resting hippocampal perfusion is increased in subje...

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Detalles Bibliográficos
Autores principales: Modinos, Gemma, Şimşek, Fatma, Azis, Matilda, Bossong, Matthijs, Bonoldi, Ilaria, Samson, Carly, Quinn, Beverly, Perez, Jesus, Broome, Matthew R, Zelaya, Fernando, Lythgoe, David J, Howes, Oliver D, Stone, James M, Grace, Anthony A, Allen, Paul, McGuire, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955214/
https://www.ncbi.nlm.nih.gov/pubmed/29440719
http://dx.doi.org/10.1038/s41386-017-0004-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955214/
https://www.ncbi.nlm.nih.gov/pubmed/29440719
http://dx.doi.org/10.1038/s41386-017-0004-6

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