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SB202190 inhibits endothelial cell apoptosis via induction of autophagy and heme oxygenase-1

Activation of the p38 mitogen-activated protein kinase (MAPK) pathway has been implicated in various detrimental events finally leading to endothelial dysfunction. The present study therefore investigates the impact of the p38 MAPK inhibitor SB202190 on the expression of the cytoprotective enzyme he...

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Detalles Bibliográficos
Autores principales: Schwartz, Margit, Böckmann, Sabine, Borchert, Philipp, Hinz, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955409/
https://www.ncbi.nlm.nih.gov/pubmed/29796178
http://dx.doi.org/10.18632/oncotarget.25234