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A case of ALK-rearranged non–small cell lung cancer that responded to ceritinib after development of resistance to alectinib
The second-generation anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitors (TKIs) alectinib and ceritinib are standard treatment options for patients with non–small cell lung cancer (NSCLC) positive for ALK fusion genes. However, almost all patients eventually develop resistance to these drug...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955410/ https://www.ncbi.nlm.nih.gov/pubmed/29796191 http://dx.doi.org/10.18632/oncotarget.25143 |