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Cytokeratin 8/18 protects breast cancer cell lines from TRAIL-induced apoptosis

TNF-related apoptosis inducing ligand (TRAIL) induces apoptosis by engaging its death receptors (DRs) 4 and/or 5 on targeted cells. Clinical attempts to stimulate this apoptotic pathway for cancer therapy, including the use of recombinant human TRAIL (rhTRAIL) or receptor agonistic antibodies, have...

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Detalles Bibliográficos
Autores principales: Bozza, William P., Zhang, Yaqin, Zhang, Baolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955420/
https://www.ncbi.nlm.nih.gov/pubmed/29796187
http://dx.doi.org/10.18632/oncotarget.25297