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Importin α5 negatively regulates importin β1-mediated nuclear import of Newcastle disease virus matrix protein and viral replication and pathogenicity in chicken fibroblasts

The matrix (M) protein of Newcastle disease virus (NDV) is demonstrated to localize in the nucleus via intrinsic nuclear localization signal (NLS), but cellular proteins involved in the nuclear import of NDV M protein and the role of M's nuclear localization in the replication and pathogenicity...

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Detalles Bibliográficos
Autores principales: Duan, Zhiqiang, Xu, Haixu, Ji, Xinqin, Zhao, Jiafu, Xu, Houqiang, Hu, Yan, Deng, Shanshan, Hu, Shunlin, Liu, Xiufan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955436/
https://www.ncbi.nlm.nih.gov/pubmed/29532715
http://dx.doi.org/10.1080/21505594.2018.1449507