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Secreted Giardia intestinalis cysteine proteases disrupt intestinal epithelial cell junctional complexes and degrade chemokines

Giardiasis is a common diarrheal disease caused by the protozoan parasite Giardia intestinalis. Cysteine proteases (CPs) are acknowledged as virulence factors in Giardia but their specific role in the molecular pathogenesis of disease is not known. Herein, we aimed to characterize the three main sec...

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Detalles Bibliográficos
Autores principales: Liu, Jingyi, Ma'ayeh, Showgy, Peirasmaki, Dimitra, Lundström-Stadelmann, Britta, Hellman, Lars, Svärd, Staffan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955458/
https://www.ncbi.nlm.nih.gov/pubmed/29726306
http://dx.doi.org/10.1080/21505594.2018.1451284