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Plasma membrane insertion of KCa2.3 (SK3) is dependent upon the SNARE proteins, syntaxin-4 and SNAP23

We previously demonstrated endocytosis of KCa2.3 is caveolin-1-, dynamin II- and Rab5-dependent. KCa2.3 then enters Rab35/EPI64C- and RME-1-containing recycling endosomes and is returned to the plasma membrane (PM). Herein, we report on the mechanism by which KCa2.3 is inserted into the PM during re...

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Detalles Bibliográficos
Autores principales: Bertuccio, Claudia A., Wang, Tony T., Hamilton, Kirk L., Rodriguez-Gil, Diego J., Condliffe, Steven B., Devor, Daniel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955555/
https://www.ncbi.nlm.nih.gov/pubmed/29768434
http://dx.doi.org/10.1371/journal.pone.0196717