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Assessing the public health impact of tolerance-based therapies with mathematical models

Disease tolerance is a defense strategy against infections that aims at maintaining host health even at high pathogen replication or load. Tolerance mechanisms are currently intensively studied with the long-term goal of exploiting them therapeutically. Because tolerance-based treatment imposes less...

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Detalles Bibliográficos
Autores principales: Hozé, Nathanaël, Bonhoeffer, Sebastian, Regoes, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955582/
https://www.ncbi.nlm.nih.gov/pubmed/29727455
http://dx.doi.org/10.1371/journal.pcbi.1006119