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Assessing the public health impact of tolerance-based therapies with mathematical models
Disease tolerance is a defense strategy against infections that aims at maintaining host health even at high pathogen replication or load. Tolerance mechanisms are currently intensively studied with the long-term goal of exploiting them therapeutically. Because tolerance-based treatment imposes less...
Autores principales: | Hozé, Nathanaël, Bonhoeffer, Sebastian, Regoes, Roland |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955582/ https://www.ncbi.nlm.nih.gov/pubmed/29727455 http://dx.doi.org/10.1371/journal.pcbi.1006119 |
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