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The HTLV-1 gp21 fusion peptide inhibits antigen specific T-cell activation in-vitro and in mice

The ability of the Lentivirus HIV-1 to inhibit T-cell activation by its gp41 fusion protein is well documented, yet limited data exists regarding other viral fusion proteins. HIV-1 utilizes membrane binding region of gp41 to inhibit T-cell receptor (TCR) complex activation. Here we examined whether...

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Detalles Bibliográficos
Autores principales: Rotem, Etai, Faingold, Omri, Charni, Meital, Klug, Yoel A., Harari, Daniel, Shmuel-Galia, Liraz, Nudelman, Alon, Rotter, Varda, Shai, Yechiel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955599/
https://www.ncbi.nlm.nih.gov/pubmed/29727445
http://dx.doi.org/10.1371/journal.ppat.1007044