Mannan-induced Nos2 in macrophages enhances IL-17–driven psoriatic arthritis by innate lymphocytes

Previous identification of the inducible nitric oxide synthase (NOS2) gene as a risk allele for psoriasis (Ps) and psoriatic arthritis (PsA) suggests a possible pathogenic role of nitric oxide (NO). Using a mouse model of mannan-induced Ps and PsA (MIP), where macrophages play a regulatory role by r...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhong, Jianghong, Scholz, Tatjana, Yau, Anthony C. Y., Guerard, Simon, Hüffmeier, Ulrike, Burkhardt, Harald, Holmdahl, Rikard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955621/
https://www.ncbi.nlm.nih.gov/pubmed/29774240
http://dx.doi.org/10.1126/sciadv.aas9864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955621/
https://www.ncbi.nlm.nih.gov/pubmed/29774240
http://dx.doi.org/10.1126/sciadv.aas9864

Ejemplares similares